Novo-A Diamond is a new generation of enhanced alkali-resistant resin independently developed by Bestchrom. The protein A ligand is expressed in E. coli. Compared with previous AT Protein A Diamond Plus, it enjoys higher tolerance towards alkali (can tolerate CIP with 0.5-1.0M NaOH) and higher binding capacity. They can effectively cut cost during scale-up by choosing lower column volume. Besides, they are suitable for capturing monoclonal antibodies or Fc fusion protein from large volume cell culture media, as well as the capture of polyclonal antibodies from ascites or plasma.

The resin has the following characteristics：

• New protein A ligands with improved alkaline stability, specific binding with IgG, Fc fusion protein and variable region of heavy chain.
• Excellent alkaline stability, allows the use of 0.5~1M NaOH for CIP and sanitization, better cost-efficiency and process stability.
• Relatively high DBC, enables efficient processing of high density feedstocks from bio-reactor.
• Stable supply, in-house production for both matrix and ligands.

For more details, please visit:  https://www.bestchrom.com/novo-a-diamond/