Biological E plans to complete production at a rate of 75 million doses of its COVID-19 vaccine Corbevax per month, anticipating over 100 million doses per month from February 2022 which will enable the city-based company to deliver 300 million doses as promised to the Centre, BE said yesterday.

Corbevax, India’s first indigenously developed protein sub-unit vaccine against the virus, received the approval from the Drugs Controller General of India (DGCI) yesterday, it said.

According to a press release issued by the vaccine maker, soon, the company plans to deliver more than one billion additional doses globally.

Biological E plans to complete production at a rate of 75 million doses per month, anticipating over 100 million doses per month from February 2022. These capacities will enable the Hyderabad-based company to deliver 300 million doses as promised to the Government of India, it said.

The vaccine has been developed by Biological E in collaboration with Texas Children’s Hospital Centre for Vaccine Development (Texas Children’s CVD) and Baylor College of Medicine (Baylor) in Houston, Texas.

Corbevax has completed two phase-III clinical trials involving more than 3,000 subjects between the ages of 18 and 80 at 33 study sites across India. The vaccine was found to be safe, well-tolerated and immunogenic, the company said.

In the pivotal phase-III study conducted with an endpoint of immunogenic superiority, Corbevax demonstrated superior immune response in comparison with Covishield vaccine when assessed for Neutralising Antibody (nAb) Geometric Mean Titers (GMT) against the Ancestral-Wuhan strain and the globally dominant Delta variant, the release said.

“Our scientists at Texas Children’s Hospital and Baylor College of Medicine are thrilled to help in the development of this vaccine, possibly the first COVID vaccine specifically designed for global health,” Peter Hotez, Professor and Dean, National School of Tropical Medicine, Baylor and co-Director, Texas Children’s Hospital Centre for Vaccine Development, said.