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Linaclotide

Category:Active Pharmaceutical Ingredients > Biochemical Ingredients > Peptides
Product Name:Linaclotide
CAS No.:851199-59-2
Standard:In-house Standards
Price(USD):0.00
Company:Hangzhou Go Top Peptide Biotech Co.,Ltd.

Basic Info

  • Grade: Research grade

    Factory Location: Hangzhou,China.

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

  • Monthly Production Capacity: hundreds of grams

    Contract Manufacturing: CRO

    Packaging Information: 1g, 5g, 10g, 20g, 50g,100g

  • Delivery Lead Time: In stock?or?2-3weeks

    Sample Provided: yes

    Payment Terms: bank transit

    Linaclotide and its active metabolite bind and agonize guanylate cyclase-C on the luminal surface of intestinal epithelium. Intracellular and extracellular cyclic guanosine monophosphate (cGMP) concentrations are subsequently increased resulting in chloride and bicarbonate secretion into the intestinal lumen. Intestinal fluid increases and GI transit is accelerated. Increased extracellular cGMP may decrease visceral pain by reducing pain-sensing nerve activity.

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