Amyloid precursor protein is made up of location on chromosome 21 long arm of the gene encoding synthesis of protein peptide chain, because of its hydrolysis after fracture, can produce a kind of composed of 40 ~ 42 amino acid called amyloid peptide chains, so called amyloid precursor protein, APP.
Acetyl - Amyloid beta/A4 Protein Precursor770 (APP) (96-110) the c-terminal and n-terminal (cyclized) a respectively by amidation and acetylated closed Amyloid precursor Protein peptide, have a pair of disulfide bond at the same time, therefore, the secondary structure is relatively stable.
Tinto biological fixation in the production of disulfide bond peptide has a wealth of experience, technical personnel first anticipation peptide properties, and then choose the suitable method to oxidation, such as air oxidation and hydrogen peroxide oxidation, iodine oxidation oxidation or DMSO.