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Abemaciclib

Category:Active Pharmaceutical Ingredients > Other Active Pharmaceutical Ingredients
Product Name:Abemaciclib
CAS No.:1231929-97-7
Standard:ChP, USP, BP, EP, JP, In-house Standards, IP, Ph. Int
Price(USD):Negotiable
Company:Quanzhou Fortune Biopharma Co.,Ltd.

Basic Info

  • Grade: Pharmaceutical Grade

    Factory Location: *

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

  • Sample Provided: no

    Payment Terms: L/C

    Abemaciclib is an oral cyclin-dependent kinase CDK4/6 inhibitor. In HR +, HER2-breast cancer cells, CDK4 and CDK6 promote phosphorylation of retinoblastoma protein (retinoblastomapChemicalbookrotein, Rb) and promote cell cycle progression and cell proliferation. Abemaciclib inhibits phosphorylation of Rb and blocks cell progression from the G1 phase of the cell cycle to the S phase, resulting in cell aging and apoptosis

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